DynaMut2 Result · RareResearch.AI Molecular Atlas
WFS1 I777T — Predicted Stability Change
Computed on AlphaFold AF-O76024-F1 v6 · Job ID 178092096659 · Biosig Lab, University of Queensland / Melbourne
ΔΔG (Stability Change)
-2.51kcal/mol
Destabilising
Mutation Details
- Chain
- A
- Position
- 777
- Wild-type
- I (Isoleucine)
- Mutant
- T (Threonine)
- Region
- C-terminal ER-lumenal (calcium binding, calmodulin, chaperone)